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Swiss Research Institute for Public Health and Addiction

PROMPT: Smartphone intervention for opioid addiction in Iran

Kurzbeschrieb Development and testing the efficacy of a guided transdiagnostic smartphone-based intervention for sufferers in opioid substitution therapy in Iran.
Projektleitung Michael Schaub
Dauer 10.2020 – 09.2024
Förderung durch / Auftraggeber Schweizerischer Nationalfonds
Kooperationspartner Afarin Rahimi-Movaghar, Alireza Noroozi (Iranian National Center for Addiction Studies; Tehran University of Medical Sciences)


Iran has one of the highest rates of opioid abuse in the world. There is currently no adequate treatment for about half of the people affected. In particular, psychosocial treatment, including for comorbid mental disorders, is often neglected. It is known from high-income countries that online tools are effective for substance-related addictions as well as mental health problems. Specifically for Iran, there are no online interventions in the addiction field adapted for the Persian context so far.


In close cooperation with the Iranian National Center for Addiction Studies and Tehran University of Medical Sciences, a Persian smartphone-based guided intervention ("PROMPT") to reduce opioid dependence and mental health problems is being developed and evaluated for effectiveness. PROMPT stands for "Promoting Recovery in Opioid Maintenance and Psychosocial Treatment." PROMPT is used in addition to standard substitution treatment in outpatient treatment centers in Tehran.


Two-arm randomized-controlled trial with opioid addicts in different treatment centers in Tehran, Iran. Comparison of experimental condition (PROMPT+substitution therapy) with control condition (substitution therapy).


The project will test for the first time whether a culturally adapted smartphone intervention is effective for treating opioid dependence and comorbid mental health problems among individuals in substitution treatment. If proven effective, PROMPT will be used as a regular psychosocial therapy module in treatment centers.


Weiterführende Informationen